基本信息
抗體名稱 rab7 (d95f2) xp(r) rabbit mab
抗體簡介 rabbit monoclonal antibody
monoclonal antibody is produced byimmunizing animals with a synthetic peptide corresponding to residues surrounding glu188 of human rab7 protein.
應(yīng)用類型 wb,ip,icc/if
反應(yīng)種屬 human,mouse,rat,monkey
抗體屬性
特異性 rab7 (d95f2) xp? rabbit mab detects endogenous levelsof total rab7 protein.
亞型 igg
保存形態(tài) liquid
儲(chǔ)存條件 store at +4°c short term (1-2 weeks). aliquot and store at -20°c long term. avoid repeated freeze / thaw cycles.
純化 affinity purified
monoclonal antibody is produced by immunizing animals with a syntheticpeptide corresponding to residues surrounding glu188 of human rab7 protein.
基因信息
基因名 rab7a
基因別名 rab7
抗原名 rab7
抗原別名 flj20819;pro2706;rab7;rab7, member ras oncogenefamily;rab7a;rab7a, member ras oncogene family;ras-associated protein rab7;ras-related protein rab-7a
抗原簡介 a member of the rabfamily of ras-related gtp-binding proteins, important regulators of vesicular transport and are located in specific intracellular compartments. rab7 has been localized to late endosomes and shown tobe important in the late endocytic pathway. in addition, it has been shown to have a fundamental role in the cellular vacuolation induced by the cytotoxin vaca of helicobacter pylori. mutations inthis protein cause charcot-marie-tooth type 2b neuropathy. note: this description may include information from uniprotkb.
抗原家族 gprotein;g protein, monomeric (rab)
抗原功能 gtpase activity;protein binding;gdp binding;gtp binding;protein transport;proteintargeting to lysosome;early endosome to late endosome transport;gtp catabolic process;small gtpase mediated signal transduction;endosome to lysosome transport;antigen processing and presentation ofexogenous peptide antigen via mhc class ii;endocytosis;epidermal growth factor ligand processing
細(xì)胞定位 golgiapparatus;intracellular membrane-bound organelle;lysosome;lysosomal membrane;late endosome;melanosome;phagocytic vesicle
分子量 23,490
抗體地址：/ab0207770.html

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